Raman, hyper-Raman, hyper-Rayleigh, two-photon luminescence and morphology-dependent resonance modes in a single optical tweezers system

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PHYSICAL REVIEW E, 72(1, 1). ONE PHYSICS ELLIPSE, COLLEGE PK, MD 20740-3844 USA: AMERICAN PHYSICAL SOC (2005) .

AMERICAN PHYSICAL SOC

Abstract

We present a setup of optical tweezers combined with linear and nonlinear microspectroscopies that enhances the capabilities of capture and analysis of both techniques. We can use either a continuous-wave (cw) Ti:sapphire laser for Raman measurements or a pulsed femtosecond Ti:sapphire laser that permitted the observation of nonlinear results such as hyper-Raman, hyper-Rayleigh, and two-photon luminescence. Only the high peak intensity of the femtosecond laser allows the observation of all these nonlinear spectroscopies. The sensitivity of our system also permitted the observation of morphology-dependent resonance (MDR) modes of a single stained trapped microsphere of 6 mu m. The possibility of performing spectroscopy in a living microorganism optically trapped in any desired neighborhood would mean that one can dynamically observe the chemical reactions and/or mechanical properties changing in real time.



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